Ryanodine
- Product Name
- Ryanodine
- CAS No.
- 15662-33-6
- Chemical Name
- Ryanodine
- Synonyms
- Ryanex;ryania;RYANADOL;ryanexel;Ryanexcel;Ryanicide;RYANODINE;bonideryatox;ryaniapowder;Ryanodine,99%
- CBNumber
- CB1480087
- Molecular Formula
- C25H35NO9
- Formula Weight
- 493.55
- MOL File
- 15662-33-6.mol
Ryanodine Property
- alpha
- D25 +26° (methanol)
- Boiling point:
- 586.95°C (rough estimate)
- Density
- 1.2805 (rough estimate)
- refractive index
- 1.6000 (estimate)
- storage temp.
- Sealed in dry,2-8°C
- solubility
- DMSO: soluble10mg/mL, clear
- form
- White solid
- Melting point:
- 219-220 °C
- pka
- 10.66±0.70(Predicted)
- color
- white to beige
- CAS DataBase Reference
- 15662-33-6
- EPA Substance Registry System
- Ryanodine (15662-33-6)
Safety
- Hazard Codes
- Xn,N
- Risk Statements
- 21/22-50/53
- Safety Statements
- 36/37-60-61
- RIDADR
- UN 3077 9/PG 3
- RTECS
- VM4025000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
N-Bromosuccinimide Price
- Product number
- 559276
- Product name
- Ryanodine, High Purity - CAS 15662-33-6 - Calbiochem
- Purity
- Naturally occurring alkaloid that blocks the release of Ca2+ from the sarcoplasmic reticulum.
- Packaging
- 500μg
- Price
- $265
- Updated
- 2024/03/01
- Product number
- 1329
- Product name
- Ryanodine
- Purity
- ≥98%(HPLC)
- Packaging
- 1
- Price
- $214
- Updated
- 2021/12/16
- Product number
- 256544
- Product name
- Ryanodine
- Packaging
- 1mg
- Price
- $466
- Updated
- 2021/12/16
- Product number
- FR30087
- Product name
- Ryanodine
- Packaging
- 1mg
- Price
- $700
- Updated
- 2021/12/16
- Product number
- FR30087
- Product name
- Ryanodine
- Packaging
- 2mg
- Price
- $1100
- Updated
- 2021/12/16
Ryanodine Chemical Properties,Usage,Production
Description
Ryania insecticide is the ground stem wood of the tropical tree Ryania speciosa Vahl., and it contains over a dozen of several structurally related alkaloids. Nowadays, this botanical preparation is of minor importance, but one of its major ingredients, ryanodine, is a widely used pharmacological tool in studies of the calcium release channels in sarcoplasmic reticulum membranes of skeletal and cardiac muscle of both insects and mammals (11,12).
Chemical Properties
white to off-white solid
Uses
Ryanodine is a potent inhibitor of Ca2+ release from sarcoplasmic reticulum with potential application towards the treatment of huntingtons disease.
Uses
Insecticide.
Definition
ChEBI: An insecticide alkaloid isolated from South American plant Ryania speciosa.
Biological Activity
Potent inhibitor of Ca 2+ release from sarcoplasmic reticulum (IC 50 values are 10 and 2.8 nM in skeletal and cardiac muscle respectively).
storage
-20°C (desiccate)
References
Rogers et ai., J. Amer. Chem. Soc., 70, 3086 (1948)
Kelly, Whittingham, Wusner., Chem. Ind., 857 (1952)
Structure:
Wiesner, Valenta, Findlay., Tetrahedron Lett., 221 (1967)
Hollstein, Rapoport.,J. Amer. Chem. Soc., 90,3864 (1968)
Wong, Hollstein, Rapoport., ibid, 90, 3866 (1968)
Wiesner., Collect. Czech. Chem. Commun., 33, 2656 (1968)
Crystal structure:
Srivastava, Przybylska., Can. J. Chem., 46,795 (1968)
Ryanodine Preparation Products And Raw materials
Raw materials
Preparation Products
Ryanodine Suppliers
- Tel
- 4401179829988
- Fax
- 4402030 700 369
- customerservice@ascentscientific.co.uk
- Country
- United Kingdom
- ProdList
- 279
- Advantage
- 60